The two teams have already met twice this season at Madejski Stadium, with London Irish taking the first 28-16 in the Guinness Premiership on 27 September, and Wasps winning the other, 24-20 in the LV= Cup on 8 November.
London Wasps have been victorious in just one of their last four games in the Guinness Premiership: 24-19 at home to Gloucester on 7 March. Wasps have also won four of their five previous Premiership games they have played on Easter Sunday.
London Irish have lost just one of their last four matches: 19-35 at Leicester on 6 March, whilst the Exiles have not won away from home in the Guinness Premiership since their trip to Bath on 28 November.
The Exiles have not achieved a Premiership double over Wasps since 2001/02.
Referee: Rob Debney (58th Premiership game)
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