Harlequins slipped back to sixth in the Aviva Premiership Rugby table following a 42-10 defeat at the Ricoh Arena and director of rugby Conor O’Shea admitted in-form Wasps were simply unstoppable.
Wasps had recorded away wins at Saracens and Bath Rugby in the previous two rounds and, with the home support behind them, ran in six tries to pick up maximum points.
Luke Wallace and Charlie Walker crossed over for the visitors but they were overrun in Coventry and O’Shea believes a few errors cost his side in a big way.
"I have to say, I thought Wasps were outstanding,” he said. “Sometimes you lose some games and we're very proud people and don't like being on the end of big loss.
"We lost a lot of collisions and we won a fair few too but the ones we lost cost us a heck of a lot more and they have a lot of bullets to fire at you.
“They are in a rich vein of form, but we will dust ourselves down and there was no doubting the work ethic going in from our players there.”
Elsewhere on Sunday, Gareth Steenson scored his 1,000th point for Exeter Chiefs as they moved to just three points behind Saracens at the Aviva Premiership Rugby summit with a 26-17 victory over Bath Rugby.
Amanaki Mafi touched down for Bath either side of the break but tries for Ian Whitten and Kai Horstmann, coupled with Steenson’s reliable boot, denied the visitors even a losing bonus point.
Harry Thacker, Lachlan McCaffrey, Jono Kitto, Tom Croft and Jean De Villiers also crossed over as the hosts moved into fourth place in the Aviva Premiership Rugby table.
Sale Sharks and Saracens played out a thrilling draw at the AJ Bell Stadium on Saturday, as Tom Arscott grabbed a last-gasp try.
Sale made a flying start, with Sam James, Johnny Leota and Arscott crossing over in the opening 15 minutes before Jim Hamilton and a Chris Wyles double hauled the visitors back into it.
Nick Tompkins and Mike Ellery nudged Saracens ahead before TJ Ioane and Arscott hit back late on – only for Danny Cipriani to miss what would have been the winning conversion.
“Overall, we've got to be satisfied to get three points at a place where a lot of teams have struggled this year," said Saracens director of rugby Mark McCall.
“Especially after we were 17-0 down, I thought we showed some good resilience and character to come back into it.
“I guess the only disappointing thing was that when we got to 36-26 up, which seemed remarkable given the start we had, it was a little bit disappointing to let them back in but they probably deserved it on the balance of play.”
Val Rapava Ruskin and Wynand Olivier each scored for the Warriors before the break but Harry Mallinder, Lee Dickson and George Pisi complemented Collins’ treble in a comfortable triumph.
And Gloucester Rugby wrapped up maximum points against Newcastle Falcons, as Billy Meakes, James Hook, Ross Moriarty and Tom Savage dotted down in a 32-6 win.
Wasps 42 Harlequins 10
Tries: Cooper-Woolley, Wade, Hughes, Young, Piutau S, Macken
Conversions: Gopperth 5, Lozowski
Tries: Wallace, Walker
Referee: Craig Maxwell-Keys
Leicester Tigers 47 London Irish 20
Tries: Thompstone 2, Thacker, McCaffrey, Kitto, Croft, de Villiers
Conversions: Burns 5, Bell
Tries: Paice, Trayfoot, Fenby
Penalty: Brophy Clews
Referee: Ian Tempest
Exeter Chiefs 27 Bath Rugby 17
Tries: Whitten, Horstmann
Conversions: Steenson 2
Penalties: Steenson 4
Tries: Mafi 2
Conversions: Homer 2
Referee: Greg Garner
Sale Sharks 36 Saracens 36
Tries: James, Leota, Arscott 2, Ioane
Penalties: Cipriani 3
Tries: Hamilton, Wyles 2, Tompkins, Ellery
Conversions: Hodgson, Spencer 3
Referee: Tim Wigglesworth
Northampton Saints 38 Worcester Warriors 18
Tries: Mallinder, Collins 3, Dickson, Pisi G
Conversions: Myler 3, Hanrahan
Tries: Rapava Ruskin, Olivier
Penalties: Heathcote 2
Referee: Matt Carley
Gloucester Rugby 32 Newcastle Falcons 6
Tries: Meakes, Hook, Moriarty, Savage
Conversions: Hook 2, Twelvetrees
Penalties: Hook 2
Penalties: Willis 2
Referee: Dean Richards