Wasps are the best team in Aviva Premiership Rugby on current form having obtained 24 league points from the last six rounds.
Their only defeat in the tournament since early October was 15-38 to Saracens in their most recent match in the competition at the Ricoh Arena on 7 January.
Exeter Chiefs have lost their last two Aviva Premiership Rugby matches, away at Newcastle and at home to Worcester, but have not lost three in a row in the same season since January 2015.
The Chiefs have lost their last three away games in all competitions since their 35-14 win at Northampton in Premiership Rugby on 23 December.
Exeter have lost only one of their last seven encounters with Wasps in all tournaments: 20-25 at Coventry in Premiership Rugby in the opening game of last season.
Wasps v Exeter Chiefs (Ricoh Arena, 3pm) Live on BT Sport
Referee: JP Doyle (146th Premiership game).
Assistant Referees: Anthony Woodthorpe & Karl Dickson. TMO: Sean Davey.
Citing Officer: Nick Wood.