The England players returning are second rower Simon Shaw, flanker Joe Worsley and centre Stuart Abbott, while Scotland wing Kenny Logan, who like the aforementioned England trio was not involved from the RWC quarter-finals onwards, also returns to club duty this week.
Shaw replaces Martin Purdy alongside partner Richard Birkett at lock, Worsley slots in at No.6, Abbott will partner Fraser Waters in the midfield, and Logan, who has retired from international rugby, will start on the left-wing, with John Rudd dropping down to the bench.
In further backline moves, to also accommodate the return of fit-again Alex King at fly-half, Mark van Gisbergen shifts to fullback, while Tom Voyce moves across to the right-wing.
Former Welsh skipper and scrum-half Rob Howley will lead the side in Dallaglio's absence.
Wasps: 15 Mark van Gisbergen, 14 Tom Voyce, 13 Fraser Waters, 12 Stuart Abbott, 11 Kenny Logan, 10 Alex King, 9 Rob Howley (captain), 8 Mark Lock, 7 Jonny O'Connor, 6 Joe Worsley, 5 Richard Birkett, 4 Simon Shaw, 3 Will Green, 2 Trevor Leota, 1 Craig Dowd.Replacements: 16 Peter Richards, 17 Mark Denney, 18 John Rudd, 19 Ben Gotting, 20 Paul Volley, 21 Tim Payne, 22 Martin Purdy.