Returning heroes Matt Dawson, Ben Cohen, Paul Grayson and Steve Thompson will have to content themselves with a seat in the stands.
Former All Black Mark Robinson returns to the starting XV after missing the previous three games through suspension following his red card in the home game against Gloucester, while James Brooks retains his place on the right-wing after scoring a try last week.
In the centres, Mark Tucker is selected in place of John Leslie, while Rob Hunter starts at lock in place of Matt Lord.
Northampton Saints: 15 Nick Beal, 14 James Brooks, 13 Chris Hyndman, 12 Mark Tucker, 11 Bruce Reihana, 10 Shane Drahm, 9 Mark Robinson, 8 Andrew Blowers, 7 Darren Fox, 6 Grant Seely, 5 Mark Connors, 4 Rob Hunter, 3 Robbie Morris, 2 Dan Richmond, 1 Tom Smith.Replacements: 16 Matt Miles, 17 Chris Budgen, 18 Jon Phillips, 19 Matt Lord, 20 Johnny Howard, 21 John Leslie, 22 Jon Sleightholme.
Kick-off: 15.00