Worsley was sent from the field after tackling 'Los Teros' winger Joaquin Pastore around the neck, but he began applauding the crowd as he walked off, while Pastore lay injured.
The 26-year-old Worsley later conceded that he was wrong to do so.
"My gesture of applause to the crowd was a misplaced one and an error of judgment," he said, "I would like to unreservedly apologise to the Uruguay squad, and fans, and wish them every success in the future."
The London Wasps flanker had earlier been publicly admonished for the incident by coach Clive Woodward.
"I've had serious words with Joe Worsley – he made a bad error and it wasn't the right thing to do, particularly as one of their players was still down," said Woodward.
"He made a bad mistake. We all make errors, but a rebuke is enough."
The Worsley incident would have been the last thing Woodward wanted following the fiasco against Samoa last week, which saw the England team mistakenly field 16 men at one time.
They were later fined £10,000 and had fitness coach Dave Reddin suspended for two matches, while referee Steve Walsh, the fourth match official at the game, also landed himself in hot water over an alleged incident in the tunnel.