He has recovered from injury and will play at fly-half with Jos Baxendell switching to centre in place of Dan Harris, who is seeing a specialist about a shoulder injury.
The only other change from the side that drew 37-37 with Northampton last week is at scrum-half where Scotland's World Cup captain Bryan Redpath has a run-out with his club side prior to travelling to Australia.
Jason White, another memeber of Scotland's World Cup squad, will be on the bench.
Sale Sharks: 15 Vaughan Going, 14 Mark Cueto, 13 Graeme Bond, 12 Jos Baxendell, 11 Steve Hanley, 10 Braam van Straaten, 9 Bryan Redpath, 8 Stuart Pinkerton, 7 Phil Davies, 6 Alex Sanderson (captain), 5 Chris Jones, 4 Dean Schofield, 3 Barry Stewart, 2 Andy Titterrell, 1 Andrew Sheridan. Replacements: Matt Cairns, Kevin Yates, Stuart Turner, Iain Fullarton, Jason White, James Hoyle, Richard Wigglesworth.
Kick-off: 15.00 (14.00 GMT)