The champions complete out-gunned their visitors, notching up five tries on their way to maximum points that go some way to closing the gap between themselves and league leaders Bath.
England World Cup hero Josh Lewsey suffered a bang to the head early in the game but got up after two minutes of treatment to score two tries in an easy victory at the Causeway Stadium.
The former army officer, playing on the wing, put in a commanding performance – as did the evergreen former Wales man Rob Howley who began the rout by scoring Wasps' opening try.
There were also scores for Craig Dowd and Ayoola Erinle, and Alex King weighed in with five conversions and two penalties.
ing set the home side on the way with two penalties in the opening 20 minutes and it took a strong tackle from Richard Haughton to deny Tom Voyce a try.
Lewsey showed just how fit he was in the 33rd minute when he saw an opportunity on the left and scooped up a loose ball to go over.
That score helped Wasps take a 20-0 lead into the interval and Lewsey added his second try nine minutes after the interval when he touched down in the corner.
Prop Dowd crashed over 10 minutes later after being pushed forward by the pack and Erinle broke clear to wrap up the scoring two minutes from time. His pace took him past both Adryan Winnan and Haughton as he raced in from 65 metres.
Sarries have consistently under-achieved over the past few seasons, and – judging by events on Sunday – will be unable shake that tag this year.
With a 17-point buffer over Rotherham at the bottom of the season they are unlikely to go down, but how a team boasting names likes Thomas Castaignede, Morgan Williams and Cobus Visagie can leak 41 points without registering one is frankly unfathomable.
They clearly pined for their absent skipper Taine Randell whose contagious mental toughness was sorely missed.
For Wasps: Tries: Howley, Lewsey 2, Dowd, Erinle. Cons: King 5. Pens: King 2.