Both sides, Tim Stimpson for Leicester and David Slemen for Quins, swapped penalties in the opening ten minutes before a second Stimpson penalty on 13 minutes gave the visitors a lead they would never relinquish.
With Martin Johnson and Austin Healey leading from the front, the Tigers were in confident move and opened their try account as Neil Back profited from a trademark Leicester rolling maul from a line-out.
Stimpson nailed the conversion to put Leicester 13-3 ahead but Quins had their chances to significantly cut the deficit before the half-ime break, Slemen was only on target for one of this three efforts.
After the break, it remained a hard-fought affair but once winger Steve Booth had crossed for the game’s second try it was all Leicester.
Jamie Hamilton added a third ten minutes before the end before Stimpson ended a good day for both him and Dean Richards’ side by scoring their fourth try for the all-important bonus point deep into injury-time.
NEC HarlequinsPens: Slemen 2
Leicester Tigers Tries: Back, Booth, Hamilton, StimpsonCons: Stimpson 2Pens: Stimpson 2