Veteran Andrews, the most-capped Springbok forward of all-time, has been a tremendous influence on Newcastle since joining them last season and his dismissal in the 66th minute – for allegedly dropping his knee on Pat Sanderson's head – was the undoubted turning point in this game.
Andrews' red card came just six minutes after England Sevens star Ben Gollings had touched down, putting the Falcons back into a game that Harlequins eventually won through a fantastic goal-kicking effort by their Irish fly-half Paul Burke, who kicked six penalty goals – and the sending off of Andrews.
Burke had earlier seen Quins into a 9-3 half-time lead, which soon became 12-3 early in the second stanza, with a single Gollings penalty all that Newcastle had to show until the one-hour mark when the self-same Gollings scored the only try of the entire 80 minutes.
Harlequins never looked like scoring a try of their own and were happy to rely on Burke's boot, giving them their fourth win from five starts this season. Quins are currently in second place on the Zurich Premiership standings, four points below Bath, while the Falcons find themselves in sixth place – six points behind Harlequins, who have 18 points.
For Harlequins:Pens: Burke 6
For Newcastle:Try: GollingsPens: Gollings 2