Harlequins have lost their last two Aviva Premiership Rugby matches, to Saracens and Exeter Chiefs, but have not lost three in a row in the tournament since February 2016. The Londoners have won only one of their last five fixtures at Twickenham Stoop in all tournaments: 53-17 over Newcastle Falcons in Premiership Rugby on 25 March.
Wasps have won their last five Aviva Premiership Rugby encounters since their 28-34 reversal at Sale on 19 February – their only defeat in the competition since mid-November.
Wasps have lost only one of their last five fixtures against Harlequins in all competitions: 21-26 in this equivalent fixture in round 1 last year. Wasps’ only victory at Twickenham Stoop in Premiership Rugby since 2007 was by a single point in February 2013.
Twickenham Stoop, 7.45pm – Live on BT Sport
Referee: Wayne Barnes (182nd Premiership game).
Assistant Referees: Paul Dix, Simon McConnell.
TMO: Sean Davey.