Saracens have won three of their last four matches against Newcastle in all competitions.
Saracens have lost their last four matches in all competitions and have picked up just eight league points from their last six Guinness Premiership matches.
Newcastle Falcons are winless in their last six games since beating Petrarca Padova 20-3 at Kingston Park in the European Challenge Cup on 22 January. Falcons have not won on the road in the Guinness Premiership since a 12-6 victory at London Wasps on 3 January.
The Falcons have won just twice in 15 previous visits to Vicarage Road.