Saracens have won their last four fixtures against Sale since the Sharks were victorious 18-15 at Edgeley Park 12 September 2008.
Sale Sharks were defeated 21-54 at Welford Road on Monday – the first time the Sharks had conceded a half century of points in any game since 2004. Sale have slipped to five straight defeats in all competitions.
Saracens beat London Wasps 13-6 at Wembley Stadium on Boxing Day – their third win in their last four encounters. Saracens have a won four, lost three record in their last seven away games this season.
Referee: Dave Pearson (149th Premiership Game)
Live on ESPN HD.