Sale Sharks drew 34-all at Worcester on Saturday but their only victory in the opening four rounds Aviva Premiership Rugby was when they entertained Harlequins in round 2.
The Sharks have lost three of their last five matches at AJ Bell Stadium in all tournaments.
Leicester Tigers’ solitary reversal so far this season came when Wasps visited Welford Road on 10th September. The Tigers have won their last two away games in Aviva Premiership Rugby but have not won three in a row on their travels in the competition since March 2014.
Sale achieved a Premiership Rugby double over Leicester last season for the first time since 2007/08 whilst the only other occasion that they have ever beaten Tigers in three successive fixtures was between 1974-76. Tigers record at AJ Bell Stadium is won three, lost one.
AJ Bell Stadium, 2.30pm
Referee: Craig Maxwell-Keys (22nd Premiership game).
Assistant Referees: Wayne Falla & Peter Allan.
TMO: Geoff Warren.