The last five meetings between the two clubs in all competitions have all gone the way of the home side on the day.
Sale Sharks have won just one of their last eight Aviva Premiership Rugby contests: 28-22 at home to Saracens on 2 January. The Sharks have lost their last two games at Edgeley Park in all competitions.
Leicester Tigers lead the Premiership table and have put together a sequence of eight successive victories in the competition since their 12-19 reversal to Gloucester at Kingsholm on 30 October – this represents Tigers best Premiership run since season 2001/02.
Leicester have won only once in seven previous visits to Edgeley Park: 26-25 on 6 April 2007.
Referee: Tim Wigglesworth (31st Premiership game)