Northampton have won their last three encounters with Gloucester, including a 27-14 victory in the Premiership at Kingsholm on 19 September and a 30-24 win in the final of the LV= Cup at Worcester on 21 March.
Northampton Saints’ only defeat in their last eleven encounters in the Guinness Premiership was 6-13 at Harlequins on 20 February.
The Saints have won their last dozen home games in the Premiership since Newcastle were victorious, 19-13, at Franklin’s Gardens on 28 February 2009.
Gloucester Rugby’s last seven games in the Guinness Premiership have all been won by the home side on the day.
Gloucester have been victorious in just one of their last 15 Premiership away games: 26-10 at Leeds on 4 October.
Saints have not achieved a Premiership double over Gloucester since season 2000/01.
Referee: Andrew Small (41st Premiership game)