The Saints have a perfect played ten, won ten record at home in the Guinness Premiership this season and are bidding to go through a complete campaign in the top flight unbeaten at home for the first time.
Saracens have won three of their last four games in the Guinness Premiership, more than doubling their try tally for the entire Premiership season in the process.
Northampton Saints visit Bath on Tuesday.
Sarries 30-19 victory at Sale on 9 April ended a five game winless run away from home in the Premiership.
Saracens have already visited Franklin’s Gardens twice this season in the LV= Cup, losing on both occasions, 3-19 and 20-31.
Sarries however, won 19-16 when the two teams clashed at Wembley Stadium in round two of the Guinness Premiership.
Referee: Chris White (177th Premiership game)