Sale have won just one of their last seven encounters against the Saints in all competitions: 24-18 at Edgeley Park on 25 April 2009.
Northampton Saints have won their last two games against Leeds and Wasps, whilst their 39-3 victory over Wasps on Sunday was their biggest Premiership win for five years.
Sale Sharks’ ended a six match losing run in all competitions with their 15-12 victory over struggling Leeds on Friday. The Sharks have not won back to back Premiership encounters since November 2009. Sale’s only away win in Aviva Premiership Rugby this season was 6-3 at Leeds in round six.
The Sharks have not won at Franklin’s Gardens since 6 May 2006.
Referee: David Rose (85th Premiership game)
Live on ESPN HD.