Wasps won a thriller 25-24 when the two clubs met in round five at Edgeley Park and have not achieved a Premiership double over the Sharks in the regular season since 2003/04.
London Wasps have lost their last five matches – their worst run since season 2001/02. Wasps have lost their last three home games, although the first of these was taken to Abu Dhabi.
Sale Sharks have also been defeated in their last five encounters in all competitions, whilst the Sharks have not won an away Premiership encounter at anywhere other than Headingley since they visited Worcester on 31 January 2009.
Referee: Dave Pearson (151st Premiership game)