London Wasps have lost seven successive matches in Aviva Premiership Rugby – their worst ever run in the competition. Their most recent Premiership victory was 14-12 at Worcester on 28 October.
Exeter Chiefs’ only loss in their last six matches was 3-31 at Bath in the Anglo-Welsh Cup on 5 February.
The Chiefs have won four of their last six fixtures in Aviva Premiership Rugby, and five of their last six away games in all competitions.
Exeter have already beaten Wasps twice this season: 21-11 in the Premiership in round four and 30-16 in the Anglo-Welsh Cup at Adams Park on 28 January.
Referee: Dave Pearson (158th Premiership game)