Wasps won 17-15 at The Rec in the Premiership in September, whilst Bath have the edge when the two teams have met at Twickenham, securing three wins to Wasps one.
London Wasps have won their last three games in all competitions, and have won on their last three visits to Twickenham.
Bath Rugby entertain Northampton Saints on Tuesday evening. Bath’s 20-43 defeat at Leicester in their most recent away encounter ended a four game winning run on the road in the Guinness Premiership.
Bath have not won at Twickenham since beating Leicester there in the Pilkington Cup final in May 1996.
Referee: Wayne Barnes (79th Premiership game)
Live on SkySports HD.