The last five encounters between the two clubs have all been won by the "home" team on the day, whilst Saracens have won just once at Madejski Stadium since 2004: 22-7 in the Premiership on 23 March 2007.
London Irish have lost just one of their last six matches in all competitions: 11-15 at home to Newcastle Falcons on 22 November. The Exiles however, have not won at Madejski Stadium in the Guinness Premiership since their 18-12 victory over Leicester there on 24 October.
Saracens have not lost in their last six games in all competitions since their 3-19 defeat to Northampton in the LV= Cup on 14 November. Sarries remain the only unbeaten side in the Guinness Premiership.
Referee: Dean Richards (28th Premiership game)