Leicester are unbeaten in their last 13 matches against Harlequins in all competitions since Quins won 26-23 in the semi-final 1st leg of the Zurich Wildcard at the Stoop on 14 May 2003.
Leicester Tigers have suffered just one defeat in their last ten matches in the Guinness Premiership: 3-19 at Northampton on 27 February. The Tigers have won their last 19 home games in the competition – currently the third best home winning run in Premiership history.
Harlequins tripped up, 18-37, against Saracens at Wembley Stadium on Saturday, and have not won away from home in the Guinness Premiership since a visit to Leeds Carnegie on 4 December.
Harlequins most recent win at Welford Road was 13-12 in the old Division One on 26 April 1997.
Referee: Tim Wigglesworth (22nd Premiership game)