Saracens have won their last three encounters with Harlequins and have also won on three of their last four visits to the Twickenham Stoop.
Harlequins have reached the final of the European Challenge Cup following their superb victory in Munster on Saturday, and have now won three of their last four matches in all competitions.
Saracens have already secured a home Aviva Premiership Rugby semi-final spot, and have won their last ten matches in all competitions, the club’s best run in competitive rugby since season 1988/89.
Referee: Tim Wigglesworth (34th Premiership game)
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