Wasps won 26-15 when the two teams met in the Guinness Premiership in round one, a match which was also played at Twickenham, marking only the third occasion in Premiership history that both regular season encounters have been played at the same venue – following Harlequins v London Scottish at the Stoop in 1998/99 and Harlequins v London Irish also at the Stoop in 1999/2000!
Harlequins have lost just one of their last four encounters in the Guinness Premiership: 17-26 at Northampton Saints on 21 November. Quins have won just two of six previous Premiership matches at Twickenham.
London Wasps have won five of their last six matches in all competitions and have also won on three of their last four visits to “HQ”.
Referee: Dave Pearson (134th Premiership game)
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