Saracens have won their last three encounters with the Sharks, whilst Sale have won just once in 14 previous visits to Vicarage Road: 40-32 on 25 September 2005.

Exeter have not beaten Leicester since a 6-0 victory at the old County Ground in April 1966, whilst the Chiefs only previous win at Welford Road was when they defeated Nottingham there 42-11 last November in the Championship.

Gloucester have won their last six encounters with Leeds, whilst the Yorkshiremen's only previous victory at Kingsholm was 33-15 on 9 April 2005.

The home side has not won in the last four clashes between Bath and London Irish.

The last four matches between the two clubs have been won by the home side on the day. Northampton have not beaten Harlequins at the Stoop since September 2004, but did win the 2009 European Challenge Cup there, beating Bourgoin 15-3.

Newcastle's only victory in their last nine meetings with Wasps in all competitions was 12-6 at Adams Park in the Premiership on 3 January.

Northampton earned the early-season East Midlands bragging rights as tries from props Soane Tonga'uiha and Brian Mujati paved the way for an opening-round Aviva Premiership Rugby win over champions Leicester at Franklin's Gardens.

Bath established their Aviva Premiership Rugby title credentials with a comfortable bonus-point victory against Leeds at a sunkissed Headingley Carnegie.

Mark Van Gisbergen and Nick Evans earned a London derby draw for their teams with a magnificent seven kicks apiece in a 29-29 Twickenham thriller.

Exeter produced a stunning performance to deservedly open their Aviva Premiership Rugby campaign with a 22-10 victory over Gloucester.

London Irish turned on the second-half afterburners at Twickenham to complete a 33-16 bonus-point victory and put an early dent in Saracens' Aviva Premiership Rugby title hopes on Saturday.

Sale opened the new Aviva Premiership season Rugby with a comprehensive win over Newcastle at Edgeley Park to mark head coach Mike Brewer's first game in charge in fine style.

The last four encounters between the two teams in the Premiership have all been won by the home side on the day.

The two clubs also met in the final round last season with Bath victorious 39-3 at The Rec. Bath have won their last five matches against Leeds in all competitions.

London Wasps have won their last three encounters with Harlequins and have also won on both previous occasions that the clubs have met at Twickenham.

In five of the last six encounters between the two teams the defeated side has obtained a losing bonus point.