Anthony Watson will start his first international for England in Saturday’s QBE International against South Africa at Twickenham (2.30pm, live on Sky Sports HD).
Watson replaces Bath Rugby team-mate Semesa Rokoduguni on the right wing in the only change to the starting line-up from the match against New Zealand.
Dylan Hartley and Courtney Lawes (both Northampton Saints) have successfully completed the Graduated Return To Play protocol and will take part in today’s training session.
England Head Coach Stuart Lancaster said: "Anthony has been pushing hard for a while and has been in impressive form for Bath and in training with us. It was great that he got on against New Zealand and we feel he is ready to start. Equally, it’s good to have Marland back in the match-day 23.
"Congratulations to Danny Care who will be winning his 50th cap. It’ll be a special moment for him and I am sure he will rise to the occasion.
"I know the players are looking forward to the challenge. South Africa have quality and experience across the park and it will be a big test for us."
England (v South Africa, QBE International, Saturday, November 15, 2.30pm, live on Sky Sports HD)
15 Mike Brown (Harlequins, 30 caps)
14 Anthony Watson (Bath Rugby, 1 cap)
13 Brad Barritt (Saracens, 19 caps)
12 Kyle Eastmond (Bath Rugby, 5 caps)
11 Jonny May (Gloucester Rugby, 8 caps)
10 Owen Farrell (Saracens, 26 caps)
9 Danny Care (Harlequins, 49 caps)
1 Joe Marler (Harlequins, 23 caps)
2 Dylan Hartley (Northampton Saints, 58 caps)
3 David Wilson (Bath Rugby, 38 caps)
4 Dave Attwood (Bath Rugby, 13 caps)
5 Courtney Lawes (Northampton Saints, 33 caps)
6 Tom Wood (Northampton Saints, 31 caps)
7 Chris Robshaw (Harlequins, capt, 29 caps)
8 Billy Vunipola (Saracens, 11 caps)
16 Rob Webber (Bath Rugby, 9 caps)
17 Matt Mullan (Wasps, 6 caps)
18 Kieran Brookes (Newcastle Falcons, 3 caps)
19 George Kruis (Saracens, 1 cap)
20 Ben Morgan (Gloucester Rugby, 24 caps)
21 Ben Youngs (Leicester Tigers, 39 caps)
22 George Ford (Bath Rugby, 3 caps)
23 Marland Yarde (Harlequins, 5 caps)