Sarries' 23-14 victory over Bath Rugby on the final day of the regular season at Allianz Park saw them finish top of the Aviva Premiership table for the first time ever.
They will now welcome Northampton Saints to the same arena for the second of the two semi-finals with Harlequins travelling to Leicester Tigers to kick off the play-offs.
Saracens have entered the play-offs for the past three Aviva Premiership seasons - losing in the final in 2010, winning the final in 2011 and falling in the semi-finals last season.
However, having finally finished the regular season as the best club in the Aviva Premiership - this season Saracens won 17, drew one and lost four - McCall is quietly confident.
"It is a big achievement and something we are really pleased with. Four years ago when this project started, the one thing we craved more than anything was consistency," said McCall.
"Saracens have been so inconsistent through the professional era. This will be our fourth consecutive semi-final and the first time that we have been top of the table.
"We've used 44 players during that time so it has been a real squad effort. We talked about wanting to show growth and progress as a group and there were signs that happened."
There was no change among the top four places of the Aviva Premiership on the final day of the regular season as defending champions Harlequins defeated Northampton 22-19.
Leicester beat London Irish 32-20 to end Quins' slim hopes of breaking into the top two and securing a home semi-final, Conor O'Shea's troops remaining third and Northampton fourth.
Danny Care, fresh from missing out on a place on the British & Irish Lions squad, pulled the strings for Quins as Tom Williams, Rob Buchanan and Tom Casson scored their tries.
Harlequins director of rugby O'Shea saw none of his players selected for the Lions but he believes scrum-half Care could yet feature on the tour of Australia.
He said: "We certainly feel he [Care] should be there but, if he can keep fresh and maintain his form, history has often shown that players left at home get called up for Lions tours."
Meanwhile Exeter Chiefs cemented their place in the top six and therefore Heineken Cup rugby next season with a late win over Gloucester Rugby at Sandy Park.
Gareth Steenson slotted a late penalty to make it 40-39 and Chiefs head coach Rob Baxter wants securing Heineken Cup rugby to become a regular achievement.
"We have moved forward, we have the chance to double-up on the Heineken Cup now, which is very important," said Baxter.
"The successful teams in the Heineken Cup, they get there not now and again - they get there regularly. For us to be there again is a big boost to how we want to develop as a side."
Sale Sharks ended their season with a 21-10 victory over London Wasps while London Welsh ensured Worcester Warriors went the whole campaign without winning away.
Welsh ran out 33-22 winners to keep the Warriors winless on the road in the Aviva Premiership this season with head coach Lyn Jones made up with the result.
"We are really delighted to finish the season on a deserved victory," he said. "We targeted six wins and we got five.
"There were several games that we lost by a point, but full credit to our players, they've given everything they've got."
The Aviva Premiership Rugby final has sold out for the last five years. To snap up one of the remaining tickets go to ticketmaster.co.uk or call 0844 844 0444
Exeter Chiefs 40-39 Gloucester Rugby
Tries: Mumm, Welch, Penalty
Conversions: Steenson 2
Penalties: Steenson 7
Tries: May, Sharples, Trinder, Cook, Burns
Conversions: Burns 4
Penalties: Burns 2
Referee: Greg Garner
Harlequins 22-19 Northampton Saints
Tries: Williams, Buchanan, Casson
Conversions: Evans 2
Tries: Elliott, Hartley, Day
Conversions: Myler 2
Referee: Tim Wigglesworth
Leicester Tigers 32-20 London Irish
Tries: Croft, Youngs, Tait, Goneva, Flood
Conversions: Flood 2
Tries: Corbisiero, Ojo, Yarde
Referee: Luke Pearce
London Welsh 33-22 Worcester Warriors
Tries: Caprice, To'oala, Arscott, Scott
Conversions: Ross 2
Penalties: Ross 3
Tries: Drauniniu 2, Abbott
Conversions: Goode 2
Referee: Matthew Carley
Sale Sharks 21-20 London Wasps
Tries: Brady, Braid
Penalties: Macleod 3
Tries: Wade 2
Penalties: Bell T 2
Conversions: Bell T 2
Referee: Dean Richards
Saracens 23-14 Bath Rugby
Tries: Ashton, Vunipola, Farrell
Penalties: Farrell 2
Tries: Webber, Agulla
Conversions: Heathcote 2
Referee: Martin Fox