Jim Mallinder's side, who beat Gloucester Rugby 30-24 in a five-try thriller at Sixways, have been drawn at Vicarage Road on the weekend of November 6.

The teams met in the semi final in March, which the Saints won 31-20, and Terry Burwell, LV= Cup Director, said: "Last season's tournament produced some great rugby and, in the final, one of the stand out games of the season.

"We are very much looking forward to the second year of a competition structure that not only helps players, coaches and officials develop but also provides more revenue potential for Premiership Rugby clubs and the Welsh regions.
"We have a committed broadcaster in Sky Sports for the next five years, plus coverage in Wales from S4C, and we would like to thank LV= for supporting the Rugby Football Union, Premiership Rugby, the Welsh Rugby Union and the teams themselves in the delivery of elite knockout rugby."

David Radford, LV= Group Marketing Director, said: "LV= is strongly committed to rugby and our sponsorship of the Anglo-Welsh tournament. We are looking forward to another year of high quality, competitive rugby."

English clubs have been allocated to the pools depending on their finish in last season's Premiership, while Welsh regions have been allocated to the pools to avoid repeating fixtures from the Heineken and Amlin Challenge cups where possible
Teams in Pool 1 play teams in Pool 4 and teams in Pool 2 play teams in Pool 3
Each team plays four pool matches - two home and two away - with the top team from each pool qualifying for the semi finals.

Pool 1
Leicester Tigers
London Wasps
Newcastle Falcons
Cardiff Blues

Pool 2
Saracens
London Irish
Leeds Carnegie
Dragons

Pool 3
Northampton Saints
Gloucester Rugby
Sale Sharks
Scarlets

Pool 4
Bath Rugby
Harlequins
Exeter Chiefs
Ospreys


Round 1 (weekend of November 6, 2010)
Bath Rugby v Cardiff Blues
Exeter Chiefs v London Wasps
Newcastle Falcons v Ospreys
Leicester Tigers v Harlequins
Sale Sharks v London Irish
Saracens v Northampton Saints
Dragons v Gloucester Rugby
Scarlets v Leeds Carnegie

Round 2 (weekend of November 13, 2010)
Harlequins v Newcastle Falcons
London Wasps v Bath Rugby
Cardiff Blues v Exeter Chiefs
Ospreys v Leicester Tigers
Gloucester Rugby v Saracens
Leeds Carnegie v Sale Sharks
Northampton Saints v Dragons
London Irish v Scarlets

Round 3 (weekend of January 29, 2011)
Exeter Chiefs v Leicester Tigers
London Wasps v Harlequins
Bath Rugby v Newcastle Falcons
Cardiff Blues v Ospreys
Leeds Carnegie v Gloucester Rugby
Sale Sharks v Dragons
London Irish v Northampton Saints
Scarlets v Saracens

Round 4 (weekend of February 5, 2011)
Leicester Tigers v Bath Rugby
Newcastle Falcons v Exeter Chiefs
Ospreys v London Wasps
Harlequins v Cardiff Blues
Gloucester Rugby v London Irish
Saracens v Sale Sharks
Northampton Saints v Leeds Carnegie
Dragons v Scarlets

Semi finals (weekend of March 12, 2011, venue TBC)

Final (weekend of March 19, 2011, venue TBC)

If the winner of the competition is an English club, they will qualify for the following season's Heineken Cup